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Neomedrol
Neomedrol Online

Basic Information:

For control of acne vulgaris in the adolescent and young adult. Also in some cases of acne rosacea and seborrheic dermatitis.

Information:

Contra-Indications
In tuberculosis of the skin, herpes simplex, vaccinia, varicella and in other cutaneous infections which do not respond to neomycin. Known hypersensitivity to any of the components.

Precautions
Avoid contact with eyes. If signs of irritation or sensitivity develop, application should be discontinued. As with any antibiotic containing product, overgrowth by resistant organisms may occur, particularly monilia. If this occurs, discontinue treatment and institute appropriate measures. Articles in current medical literature indicate an increase in the incidence of patients allergic to neomycin. The possibility of such a reaction should be borne in mind.

If extensive areas are treated or if the occlusion technique is used, the possibility exists of increased absorption of the corticosteroid and suitable precautions should be taken. The prolonged use of antibiotic-containing preparations may result in overgrowth of nonsusceptible organisms, particularly fungi. If new infections appear during treatment, appropriate therapy should be instituted.

Convulsions have been reported with concurrent use of methylprednisolone and cyclosporine. Since concurrent administration of these agents results in a mutual inhibition of metabolism, it is possible that convulsions and other adverse events associated with the individual use of either drug may be more apt to occur.

Ototoxicity and nephrotoxicity have been reported following absorption of topically applied neomycin.

Pregnancy
Although topical steroids have not been reported to have an adverse effect on pregnancy, the safety of their use has not absolutely been established. Therefore, use with care during pregnancy.

Children
When topical corticosteroids are applied for a prolonged period of time, sufficient systemic absorption can suppress the hypothalamic-pituitary-adrenal axis. Growth suppression may also occur.

Adverse Reactions
The following local adverse reactions have been reported with topical corticosteroids, either with or without occlusive dressings: burning sensation, itching, irritation, dryness, folliculitis, secondary infection, skin atrophy, striae, hypertrichosis, acneiform eruptions, allergic contact dermatitis, laceration of the skin and hypopigmentation. tag_DosageDosage

Dosage: After careful cleansing of the affected skin to minimize the possibility of introducing infection, Neo-Medrol Acne Lotion should be applied sparingly to the affected areas once or twice a day initially. Care should be taken to avoid contact with the eyes. The frequency of application will vary from patient to patient, depending on their susceptibility to the drying effect of the lotion, and may have to be reduced to every other day in some patients.

 

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